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How long do amphetamines stay in your system?

Half of the amount of amphetamine that you take is eliminated by your body in under 11 hours (amphetamine elimination half life). But heavy and chronic amphetamine use can be detected in your system up to one week after your last dose. Learn more about how long the effects of amphetamine last, amphetamine detection times and drug testing for amphetamines here.

How do you take amphetamines?

The most common forms of amphetamines are pills, tablets, or capsules, which are swallowed. The less frequent forms, liquid and powder, can be injected or snorted but using this routes of administration increases risk for addiction to amphetamines. This is because getting high on amphetamines increases your risk of mental dependence on them. In fact, although physical dependence on amphetamines is possible, psychological and mental dependence is more frequent and known to increase risk of amphetamine addiction.

What are amphetamines used for?

Medically, amphetamines are prescribed by doctors treating ADD and ADHD. But amphetamines have also been used to treat narcolepsy, have been prescribed as a weight loss medication, and rarely, have been prescribed to treat depression.

Peak levels and half life of amphetamines

The duration of a single dose effect of amphetamines lasts from 2 to 4 hours. Residual effects of amphetamines can last longer. Peak plasma concentrations of amphetamine occur approximately 3 hours post-dose for l-amphetamine. The amphetamine metabolite peaks at 12 hours.

The mean elimination half-life for d-amphetamine is between 9.77-11 hours. Following intravenous injection, however, the mean elimination half-life of the amphetamine metabolite is slightly longer at 12.2 hours.

Amphetamine drug testing

How long do amphetamines stay in the body?  Detection periods for amphetamines vary. This is because rates of metabolism and excretion are different for each drug, each use and vary by individual. Approximations are due to variables such as drug metabolism and half-life, person’s physical condition, fluid intake and method and frequency of use. This is why detection periods for amphetamines should be viewed as estimates. Cases can always be found to contradict these approximations.

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In general, amphetamines (including methamphetamine) have a drug and detection period of 1-2 days in urine testing, although some sources claim to be able to detect amphetamines up to 4 days after you take them. Initial testing cutoff concentrations are at 1,000 ng/mL with a confirmation test at 500 ng/mL. Blood concentrations are generally used to distinguish therapeutic use from abuse.

False positive tests for amphetamine

Many “over-the-counter” (OTC) and prescription medicines contain chemicals that are structurally related to amphetamine. These compounds can be identified in the standard amphetamine screening procedures or mistaken for amphetamines. In fact, the Physicians’ Desk Reference provides a list of more than 350 medications that may produce positive test results for amphetamines. If you are taking cough suppressants, antihistamines, antibiotics or other OTC or prescription medications, be sure to report these to drug testing staff. Positive test results for amphetamines can occur and you should be clear about

Amphetamines and addiction

Amphetamines can be very addictive. In fact, large doses and long term use of amphetamines can cause higher tolerance levels and dependence, which lead to addiction. Physical dependence on drugs like Adderall require detox and withdrawal periods (Adderall withdrawal how long?) So how do you know if you have problems with amphetamines or not? Well, if you think that you have a problem, you probably do. Please send us your questions, and we will help you find an answer. Feedback, comments, and experience is also welcomed in the comment section below.

Reference sources: SAMHSA/CSAT Treatment Improvement Protocols: Chapter 9, Drug Testing as a Tool
National highway Traffic Saftety Administration fact sheet on methamphetamine (and amphetamine)
FDA fact sheet on Adderall

 

 

Photo credit: Brookhaven National Laboratory

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28 Responses to “How long do amphetamines stay in your system?
Rae Ferrer
1:48 pm July 20th, 2014

My son has been on adderall for 10 yrs. Had to go cold turkey because of no insurance. It has been 3 wks since he has had these pills. He is still going through classic symptoms that I have read about. He is still on Zoloft for depression. Why is this taking so long? Headaches, tremors, agitation, nausea, sleepiness, “not feeliing good” still seeing mmost of the time. Why?

rachael
2:19 am December 1st, 2014

can i get a free home testing kit??for amphetsmines as losing every1 around me as used to use n now always being accused need to sort this urgently as really feeling depressed!!! x

3:53 pm December 9th, 2014

Hi Rachael. Yes, there are home drug testing kits, but you’d have to buy them. There is no such thing as a free home drug testing kit. But, you can talk to a pharmacist or order tests on the internet.

Tracy
7:12 pm February 1st, 2015

I’ve been taking HCG a liquid diet supplement 3yrs. on and off but yet consistently. I finally abruptly stop taking the diet supplement and I’m having all sorts of withdrawal symptoms anxiety, panic attacks, tremors, shakiness, heart palpitations,insomnia etc… for the last 30 days is there anything I can do, I’ve been prescribed canal for muscle relaxants but it’s not working is there an detox regimen for this?

Ali
5:10 am August 8th, 2015

My 8 year old has recently been prescribed evekeo, amphetamine sulphate for adhd. I’m scared to death to start him on it. He needs it mainly for concentration. I’m not sure if this is the only or best help he can get. Is he better off struggling through his school years without meds? Such a tough depiction for a parent, woe have tried other stimulants with not so great results.

P stewart
10:13 am August 18th, 2015

How long does 3-fpm stay in your system

1:50 pm August 24th, 2015

Hello Ali. I cannot give you an advise on whether or not you should start him on the medication. If you need further guidance or information, please consult a doctor that will be able to answer all your questions.

Richard
6:49 pm August 28th, 2015

I had used amphetamines recreationally once when being prescribed bupranorphine(subutex) & due to the low ceiling point(max effect)of subutex,I assume my body stored pockets of the drug perticularly in kidneys(urine was hard to pass)tested positive 7days after a small dose! if you dont pee it will remain.

Shae
9:40 pm September 12th, 2015

I have been taking the futures banned substance dendrobium it’s in the pre work out I used craze! I didn’t realized that it was an amphetamine till it was too late and I took it. I’m trying to bulk up to go into the military but if I come up positive for meth haha yea I can say goodbye to that dream I need help! I’m not dependent on it, I’m 135lb women who works out often and lots of hydration will I be okay

Justin
7:02 pm October 3rd, 2015

I take Vyvanse for ADD, but have completely lost my appetite. Its been over 24 hours since I last took one, but still cant eat. It takes effort to even swallow, like my body is rejecting it. How long will it be until I regain my appetite?

5:13 pm October 9th, 2015

Hello Justin. Have you told your doctor about this issue yet? Side effect such as yours should be reported to medical professionals immediately. It may be the dose you are taking, or you may need to be switched to another medication. Anyway, what is happening is not normal and should not be left unattended.

Russell
9:28 pm November 4th, 2015

Well I was in rehab and I tested hot for meth/ice when I got ther and once a week I was tested then I got called in for a conference by the staff and consoulers and they told me I wasn’t in trouble and they knew I wasn’t useing but it took over four (4) weeks befor the drug was out of my system!

William V.
1:45 am December 18th, 2015

I have been taking adderall on and off for the past 6 years. I have never been prescribed it not have I ever used the drug for more than a few says at time. Actually I only typically use it roughly every few months or so. Nonetheless, I used the drug for dart or so and stopped. It was 5 days later I was given a ua at thus methadone clinic I belong to and adderall DID soiree up

Ellen
6:59 pm December 20th, 2015

Hi I have a friend who takes ampetamine and would like to know if she went to the doctors if they would prescribe her anything as she is a long term user, and what help is available.
Worried friend.

Lydia @ Addiction Blog
10:59 am December 21st, 2015

Hi, Ellen. Your friend may talk with the doctor about her amphetamine use first, so s/he would find suitable therapy for her.

ma
3:59 am December 30th, 2015

Can thiz show up in a.urine drug .test

Lydia @ Addiction Blog
2:55 pm December 30th, 2015

Hi, MA. Yes, amphetamine can show up in urine drug testing up to 1-2 days after the intake.

Erica
5:30 pm January 18th, 2016

Im 180 female. I take a weightloss stack of 200mg of caffeine and a OTC called BRONKAID. It has 25 mg of ephedrine sulfate. I drink up to 1 to 1.5 gallons of water a day and do high intensity workouts ( 4-6 miles cardio and circuit weight training) I have a drug test coming up in the next week. Will this be in my system as amphetamines?

adams
3:56 pm January 22nd, 2016

hello.. i just want to ask some question about amphethamine….i have ever used it for once in my live…it is because my friend proposed it to me for sex…this story is about 2 months ago…my question is does the amphetamine still in my system or my urine? next week i will be attend to urine testing…i am worried about this problem..i hope you can answer my that question and give any tips for me pass the test…..i’m waiting for your answer..thank you…..

Sharon
10:46 am January 23rd, 2016

Last amphetamine I took was last Friday I ad a swab done yesterday Wil it show up it was only a Crum

Lisa
3:15 am February 16th, 2016

My friend had a blood test maybe in a few days. She took .0125 grams amphetamine for the first time. How long before it leave her bloodstream and urine? Does it depend on weight and height. She about 130 and 5’4.

Rabbie b
10:27 am February 21st, 2016

Hi I took amphetamine last night,not a lot about a finger full amount of base and immediately regretted it and made myself sick roughly 3mins later.will it still be in my system?i didn’t feel any high and fell asleep roughly half an hour after taking it.

Miranda
6:09 am February 24th, 2016

My friend doesn’t use very often but had a smoke 4 days ago will it come up in a urine test

Chantelle
3:16 am February 28th, 2016

I’m only 18, I took dexi’s for the first time on Friday, I took 4 straight up then drank heavy that night, I took another 6 last night and also drank heavy.. I have slept 6 hours not straight in 48 hours and I have mental illnesse’s and I’m getting hot and cold, a really dry mouth no matter how much water I drink and I can’t sleep, I have stomach pains, feel sick and agitated and emotional as hell.
What do I do?

Linz
11:52 am March 9th, 2016

Hi
My name Linz the past 4 years iv bin having a tiny bit of Amphetamines in a morning.
I don’t take it any other time a day just the morning,
I think it come to having a problem, so I decided to stop I’m on my 5th day today of not taking any will this effect me or do I have to ween my self off
Thanks

Shelley
8:26 pm March 20th, 2016

Hi I have been taking street Anphetamins for years and I want to stop but I have no energy without it , I can’t cope going to work without it please help

How long does speed stay in your system for a drugs test for sweat and saliva
2:59 am April 13th, 2016

How long does speed stay in your system for a drugs test for sweat and saliva.
Please answer as soon as you can.
Thank you

Young mama
9:38 pm May 2nd, 2016

Hi, I used roughly 15-20 speed (ice) pills over a 48 hour time frame, I’m on programs and they will give me a urine soon, how long will it be there? And how could I help speed up the process… I’ve been struggling to stay sober and had the weekend without my baby and well we all know how that went …. Concerned mom

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