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Ecstasy long term effects

The immediate effects of ecstasy vary and depend on a persons size, weight, general health state, whether they have a tolerance to ecstasy, and whether other substances (prescription meds, illicit drugs, and/or alcohol) are taken around the same time.

What are the long term effects of ecstasy use? How can taking ecstasy long term damage your health? In the long run, there is no safe amount of ecstasy to be used. Over a prolonged period of time, ecstasy changes a person’s brain chemistry and can seriously damage the function of crucial body organs. More about the long term effects of ecstasy here, with a section at the end for your questions and comments.

Long term effects of ecstasy use

MDMA produces long-term deficits in serotonin function in the brain. Serotonin function is an implicated cause of many psychiatric disorders which include depression and anxiety. This suggests that ecstasy users may experience more psychopathology than non-users. Moreover, evidence from studies on monkeys show that even seven years after a brief exposure to ecstasy, serotonin levels in monkeys’ brains have not fully returned to normal. We give examples of animal studies because of the poor number of tests on human brain damage.

Ecstasy use has been linked to some serious physical injuries such as liver, kidney and heart problems, as well as significant immune system weakening from staying awake for long periods of time and stressing the body.

Long term effects of ecstasy on the brain

When people use ecstasy chronically over a longer period of time, there may be changes in their brain chemistry that suggest that the serotonin neurons are damaged. One major clue is that serotonin itself and its metabolites are diminished in the brain. Long-lasting brain side effects from ecstasy can affect your thought and memory. Other CNS (central nervous system) damages from ecstasy use, include:

  • brain damage
  • convulsions
  • degenerated nerve branches and nerve endings
  • dependency syndrome
  • drug craving
  • reduction of overall brain mass

Just like other similar mind-altering substances, the use of ecstasy has been associated with impaired mental health and impaired judgement. Heavy ecstasy users experience a number of psychiatric changes, which may persist for a period after cessation of the drug. These may include:

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  • anxiety
  • confusion
  • depression
  • disturbed sleep
  • disturbing emotional reactions
  • impaired memory and trouble learning
  • low mood and irritability
  • paranoid thoughts
  • scoring significantly higher on measures of obsessive traits

Long term effects of ecstasy on the body

Ecstasy is associated with extensive periods of physical activity because it’s usually used at clubs during raves or at festivals. This can lead to one of the most significant, although rare, acute adverse effects hyperthermia, or overheating. Also, dehydration, hypertension, and heart failure may occur in susceptible individuals.

Heart

Ecstasy has the ability to reduce the pumping efficiency of the heart. This side effects is of particular concern during periods of increased physical activity, such as at dance parties where the drug is most commonly used, which further complicates the problem. The long-term physical effects on the heart of using ecstasy include:

  • cardiotoxicity
  • cardiovascular collapse
  • heart failure
  • hemorrhaging
  • increase in heart rate, leading to serious complications for people with cardiovascular disease

Blood pressure

Once administered, ecstasy is rapidly absorbed into the human bloodstream where the drug’s metabolites interfere with the natural ability of your body to break it down. As a result, additional doses of ecstasy, also known as “stacking”, can produce unexpectedly high blood levels, which could worsen the cardiovascular and other toxic effects of the drug.

Kidneys

Ecstasy is toxic to the kidneys. And, in many cases recreational use of ecstasy has led to some form of medical intervention. It is indicated that the hyperthermia (increase in body tremperature) caused by ecstasy is responsible for kidney damage in users.

Liver

The numbers of ecstasy users who have suffered from liver damage as a direct cause of recreational use of the drug is small. It is believed that one of the leading causes of liver damage is a compromised immune system, which is a side effect of long term ecstasy use. However, it is still not confirmed whether liver toxicity is caused by the drug itself, or by other substances found in ecstasy tablets.

Respiratory system

Crushing ecstasy pills and insulating the powder can cause burns in your nose and mouth, which can hurt the rest of your respiratory system. Ecstasy use can also lead to collapsed lungs and/or asthma. Excessive snorting leads to:

  • damage of the nose mucose
  • common nosebleeds
  • holes in your nose
  • nose becomes soft from the drug eating the cartilage

Ecstasy effects on pregnancy and fetal development

Ecstasy has the ability to pass from the mother’s body and into the fetus through the placenta. Normal prenatal and infant development can be affected by ecstasy exposure. The use of ecstasy during pregnancy also appeared to affect the sex of the babies born; male births are more common among women who used ecstasy while pregnant.

A great concern is ecstasy’s properties for depleting the level of serotonin, which is important for gross motor control among other functions. Early in fetal development, serotonin plays a vital role in brain formation.

Ecstasy use during pregnancy can lead to:

  • altered brain development in the first trimester
  • newborn behavior changes
  • delaying of the normal motor functions in the mid and late stages of pregnancy
  • long-term learning and memory problems

Long term effects of ecstasy addiction

Addicted or psychologically dependent ecstasy users report symptoms including:

  1. Continued use despite knowledge of physical or psychological harm.
  2. Tolerance or diminished response to previously effective doses.
  3. Withdrawal effects from ecstasy (fatigue, loss of appetite, depressed feelings, and trouble concentrating).
  4. Failed attempts to quit using ecstasy.
  5. Trying to control use, but ending up taking more than intended.
  6. Giving up important work, school, home and other activities due to ecstasy use.

But, the side effects of being addicted to ecstasy don’t end here. Ecstasy addiction can take its toll on your general health state, your financial stability, your relationships with close family and friends, your criminal record, etc.

Can ecstasy long term effects damage you permanently?

It is unlikely that the psychological side-effects of using ecstasy are permanent. However, research on animals (and less definitive research in humans) does point to the conclusion that taking ecstasy over the long-term may lead to lasting brain damage.

Long term effects of ecstasy questions

Got anything to ask or add? Please send us your questions and comments via the designated section at the bottom of the page. We appreciate your feedback and try to answer to all legitimate inquiries personally and promptly. In case we don’t know the answer to a question, we will gladly refer you to professionals who can help.

Reference Sources: DrugAbuse: Long-term effects of ecstasy: Neurotoxic?
DrugAbuse: Long-term ecstasy use may impair memory
DrugAbuse: Is MDMA Addictive?
NIDA: MDMA/Ecstasy Research: Advances, Challenges, Future Directions
Drugfreeworld: SHORT- & LONG-TERM EFFECTS
Mydr: Ecstasy effects on the body
Stopteendui: Short and Long Term Effects
Casemed: First and Only Study on Harmful Effects of Infants Prenatally Exposed to Ecstasy
GoAskAlice

Photo credit: Wikimedia Commons

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5 Responses to “Ecstasy long term effects
Leon
12:22 am May 5th, 2017

Hi there just read this and wanted to ask a few question..
Last year approx 7 to 8 months ago, I was using Transformers or armarni pills/ XTC…
I first two experience’s we’re fabulous to be completely honest, But on my third attempt i took it a bit too far and ended up talking 9 one after the other..
It was great at the time, But adventually after so many hours I was getting hot and cold as you do and then caught Hypethermia, My eyes went bloodshot and all around them was completely red, My insides felt like I was bleeding It was horrible, I stayed up the whole night As I couldn’t sleep..
The next day my body didn’t feel as bad, I went home as I was at a friends house, And slowly tried to recover ( with only me knowing that this had happened ) I haven’t been to see any doctor to this day.. I have been experience some really strange feelings in my head, extreme pressure, Nausea, Massive loss of memory ( To the point I can’t remember what I did after 5 minutes ) Fuzzy senation of the left side of my head which is constantly, I get really light headed pretty much all the time.. It’s dreadfull but somehow I’m still trying my best to carry on with day to day things.. I would be over the moon to recieve some information and help on what I could do maybe just to make my life a little better as I’m a bit all over the place… I have been to the doctors and they did a blood test and everything is fine on the inside, It’s just my head..
I haven’t seen a doctor and explained the symtoms as I’m not sure what to say or do… thank you very much! I will be very happy to wait for a reply, thanks, Leon…

Lydia @ Addiction Blog
12:43 pm June 7th, 2017

Hi Leon. It seems you took a lot… and all of these symptoms that you have listed are pretty serious and might cause serious damage to your health. Please be careful next time, and explore our ecstasy infographics to learn more about the effects of ecstasy.

C
12:00 pm July 6th, 2017

What is considered long term use when discussing lasting effects on brain function and memory?

Lydia @ Addiction Blog
5:30 pm July 12th, 2017

Hi C. Long term use means using the drug for a longer period of time.

Anthony
11:39 am July 15th, 2017

I went to EDC last month. Night 1 consisted of 2 orange teslas; spaced out among 4 halves.
Thinking back that’s a lot! 500mg thoughout the night! I should have stopped there for a couple of months.
Night 2, I felt like I almost died. I took 1 blue owl, a half a pink marshmallow, and then 1 Molly. I was mainly popping just to stay up at this point. I was starting to feel a little strange, but didn’t think much of it. So then I made a pretty dumb decision: chugged a margarita and drank a beer before one of the last sets of the night. Keep in mind vegas is HOT. During one of the sets I began to trip extremely hard. I felt light headed and abdomen discomfort. I knew something was wrong. I told my friend I was going to the restroom. I honestly felt like my organs were failing. I probably should have seeked medical attention. I knew I had to pee but it was so difficult to. It took me like an hour. I was losing my mind. I had to pour water on my head to keep myself from passing out. It was a terrible experience..
Night 3 came along. I felt a little better but still shook from the night before. I said I’m done rolling and was going to stay sober the whole night.. *feeling completely wiped out. I stayed sober for a few sets. All my friends had popped a while ago and seemed fine. So around 12:30 am I said fuck it and popped half a tesla. I started to roll but it felt so minimal. Probably because I had such little serotonin left. I felt like at that point I sold my soul to the devil lol. I ended up taking the other half and having a pretty decent time. Then the final set of EDC came along. I was tired but I felt alright. Then we smoke a fat blunt.. also a terrible decision on my part.. it made me feel extremely paranoid and maybe slightly schizo. I remember when we were walking back to the car after the set.. I was hearing voices, like people were saying things to me when they weren’t. Like people from the crowd it was so weird and very uncomfortable. The weed had a bad effect with the roll because of the cumulative come down.
Now it’s been about a month since and things have not been the same. I have suffered 2 extreme panic attacks. I feel foggy and spaced out. I got very sick and still am. Strep throat and bronchitis. I feel mentally unstable and slow. Looking back, I regret taking so much throughout one weekend.. I feel like I have damaged my body and my brain..

I’ve rolled before. Never had these problems.. only thing was that I had never taken such heavy amounts in a single weekend. I’d have to say I took a little less than 1000mg throughout 3 days..

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