How long does Spice last?

How long Spice lasts in your body depends on which synthetic cannabinoids are found in the Spice mixture. Its effects may last for hours to days, even weeks. More on Spice duration of action here.

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How long does Spice last?

No one really knows.

Why? Because how long Spice lasts in your body depends on which synthetic cannabinoids are found in the Spice mixture. But in general, its effects can last for hours to days or even weeks after use, while specific Spice ingredients JWH-073 and JWH-018 can be spotted in the system up to 3 days after use. More on Spice, how fast Spice works, and its duration of effects here… with a section for your questions about helping Spice addiction at the end.

What is in Spice?

Spice (synthetic marijuana) is a synthetic type of marijuana that it is made of herbal mixtures sprayed with synthetic cannabinoids. Currently, there are more than 140 cannabinoids used in Spice, but most commonly compounds are JWH-018, JWH-073, CP 47497, and HU-210. Spice produces experience similar to marijuana, and it is sold under different names including fake weed, K2, Skunk, Black Mamba, and many others.

Spice effects on the body and brain

The effects of Spice on the body are highly similar to those of marijuana and include relaxation, altered perception, and elevated mood. In some cases, the effects are more stronger and can include physical symptoms such as elevated blood pressure, elevated heart rate, diaphoresis, palpitations, and tremulousness. Some Spice users claim psychotic effects like hallucinations, paranoia, agitation, and anxiety. Others report Spice tolerance increases after days to weeks of daily dosing.

Since Spice is an herbal mixture and relatively new drug, there have been no scientific studies of its effects on the brain to date. What we know is that the cannabinoid compounds found in Spice mixture affect the same cell receptors as THC, marijuana’s main psychoactive component. However, some Spice components act more strongly on those receptors, which can trigger more powerful and unpredictable brain effects.

Spice duration of action

Usually, Spice is smoked in joints or pipes, but some users prefer making a tea from it. Spice’s effects start about 5-10 minutes after smoking the mixture. It is strong drug which produces its effects only after one or two inhales. Onset of effects for Spice teas or baked goods is around 20-40 minutes after consumption.

Spice time in the body

There is no record of how long Spice lasts in your body. It definitely depends on which cannabinoids are found in the particular mixture of Spice, and its effects may last for days. The most commonly used Spice compounds JWH-018 and JWH-73 can be detected in the human system up to 72 hours after use. Also, these synthetic compounds are not traceable in the blood or urine with a common DOT 5-7-9 or 10 panel drug test, which makes Spice attractive for many people.

How long do Spice effects last?

Since Spice is made of different components, the duration of its effects vary depending of which cannabinoid is found in the Spice mix. Nevertheless, the Spice components tend to last longer than THC. We must point out here that the duration of its effects depend upon the type of cannabinoid, dosage, and frequency of use. However, it is generally agreed that Spice effects can last up to 5 times as long as those of marijuana.

How long does a Spice high last?

The duration of a Spice high is anywhere from 1-8 hours. Some researchers have reported that an intense Spice high lasts possibly between 10-30 minutes; other reports (mostly from users) claim that the high lasts for significantly longer. What appears constant in research is the fact that it does not seem to take much more than a hit or two of the pipe to activate the Spice high.

Spice high effects

Similar to marijuana, Spice high effects include changes to perception and brain neurotransmitters, only stronger. Spice ingredients act by binding to cannabinoid receptors in the central nervous system, producing symptoms typical of marijuana usage, but with more intense psycho activity.

There are still no studies how Spice affects human body, but public health concern is that there may be harmful remains in Spice mixtures and that users are actually experimenting on themselves. So far, thousands of ER visits are made each year due to Spice overdose and related deaths have been investigated for being connected with Spice. Moreover, in 2012, a 17-year old girl suffered multiple strokes after two weeks daily use of Spice. These cases show that, after all, Spice remains a dangerous drug.

Reference Sources: Montgomery County Maryland Health and Human Services Committee on Spice
NCBI: Acute Intoxication Caused by a Synthetic Cannabinoids in Two Adolescents
OASAS NY: The problem posed by designer drugs
About the author
Lee Weber is a published author, medical writer, and woman in long-term recovery from addiction. Her latest book, The Definitive Guide to Addiction Interventions is set to reach university bookstores in early 2019.


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  1. Asking for a friend, who thought she smoked weed a few weeks ago. Took a big spliff and had worst heart palpitations few mins after high and the day after that. Stopped after a day. Last week she started to get really sick, back pain, nausea, anxiety, high heart rate.. Also getting feelings of anxiety and depression and she never has before! After looking it up, is it possible this is due to spice? could she have smoked it not knowing it wasnt cannabis?? Also for anyone who has before, do the symptoms go away?

  2. FUB-AMB was found in chronic user who claims not to have used in 2 months, is this possible, his usage was 3-4 oz. per week for many months.

  3. Yesterday around 5 some friends said if j wanted to smoke weed and said sure.but after 2 hits idk what happened and I started to heart was beating fast I was seeing things and I thought I was going to pass out .i don’t think that was weed .its around 3 now and I still feel like that .what I can I do.I’m scared.I need help

  4. Ive been using since coming out prison in april using pipes mainly n its in my brain n im so scared ive been adddicted to every drug but this something else blackoouts walking down main roads on friday nights HELP!!!

  5. Hi, the other day (2 days ago) me and my friend had a spliff what was already rolled from her boyfriend and I had a really bad do on it , I was in hospital for 7 hours in total on a heart machine , my pulse and heart rate increased double the amount of what it should be and i was very lucky i didnt have a heart attack , i also had an ecg … the more I’m starting to think, I think it was spice and not actual cannabis … I was just wondering how long it will take for me to become better as I still feel like to heart rate is faster than what it should be and still have some of the effects?

  6. Does spice effects come back in the future? For example, if you’ve stopped smoking spice 2 years ago and all of the sudden you start getting the side effects from it?

  7. I stopped smoking spice recently and i was a heavy user for about 6 months. I havent one through any of the basic withdrawal symptoms thank god but after 2 weeks of not taking any spice i started feeling my heat racing always i dont have any cravings or nothing but im really concerned about the irregular heartbeats….. MY QUESTION is will the palpitations ever stop?!!!

  8. Hello all I am here seeking for help, not for me but for my husband he has withdrawal from spice and he hasn’t smoke since a month ago it all started with sickness vomiting restless anxiety but all that is gone. Now its emotional and depression does anyone know how long does those side effect normally last and how I can help him?

  9. Someone I know inadvertently smoked some spice thinking it was pot. Over the course of a week the use went up to maybe 4 times a day. They are still having periods of paranoia, restlessness, and some auditory hallucinations. The last use was roughly 3 weeks ago. They have been to a doctor and given some meds to help smooth things out. The symptoms tend to come and go. Mornings start out pretty rough, then most of the day is pretty good. The symptoms come back around mid day for a short period. Most nights have been mostly symptom free except for a little restlessness. Loud sudden noises and crowds tend to be a bit of a trigger. Each day gets a little bit better. I wish we had answers to more questions but I’m posting here because it does get better and everyone here is looking for answers and a reason to hope. Do your best to remind yourself that time will be a major factor in the healing process. If you are concerned about yourself or someone you know, please do your best to find some help. It’s not something anyone should go through alone and you or your friends should have positive outlets. It is going to be hard but it will get better. Stay strong!

  10. I have been a daily user for the past 6 months. I found a new product that is pills. The package is labeled as 100% free cannabinoid. So basically it’s spice pills. Just took one. They have a brown powder in them. It smells like your average blend only ground into a fine powder.

  11. hey,if i was to take a drug test for probatoin tommorow and i have smoked tonight,lets just say 18 hours b4 test,would i fail it for anything?it is im pretty sure a dipstick test,it dont get sent no were just simply dumped out and thrown away when done testing.i havnt smoked any real pot for prob 3 weeks

  12. My boyfriend has been smoking this every day for the last 6 weeks, the paranoia has got so bad he has now stopped. How long until it’s out of his system?

    1. Hello B. The problem with Spice is that every package is a different blend and a different composition of chemicals. It also influences all individuals differently. So, there is no way to estimate how long the Spice-enhanced-paranoia will persist.

  13. How long can one expect to experience side effects of using spice? Supposedly a one time use about three or four weeks ago. Now having panic attacks, paranoia, hallucinations, and agitation.

    1. Hi Kimberly. I am not aware of such effect from mixing spice and caffeine. Spice is a potent drug and there is no need to enhance the high.

  14. I smoked 6g of pandoras box 3 days ago and im still having visuals and feel almost numb like its hard to move its like a mellow high now but I cant concentrate and I have bad controll of my body like im slow . How long will this last

    1. Hello Danielle. Spice withdrawal symptoms can peak in severity after 4-7 days of abstinence. In most cases, symptoms dissipate 2-3 weeks of abstinence from Spice. The psychological and emotional symptoms can last much longer if they go untreated. You can treat vomiting and chills with simple over-the-counter cold medicines or meds that treat nausea. Ask the pharmacist for best suggestions around which meds to use.

  15. Hi Cesar. That’s your body reacting to the spice. You can prevent it from ever happening againg by simply not smoking Spice.

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